Maree Tetlow, who has been chief executive of the Northern Tasmania Development Corporation since 2016, made the announcement in a statement on Thursday.

"It is with some trepidation that I advise of my decision to resign," she said. "I always intended that the role was a transitionary one."

Ms Tetlow said she joined the organisation - owned by seven Northern councils - to help with its establishment, and saw an opportunity to hand over the role after the regional economic development strategy is finalised in December. A draft was released earlier this month.

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She thanked all who had worked with her on the "team effort", and said the NTDC's next stage would involve working with stakeholders to "implement priority actions."

"I am fortunate to have worked with a lot of stakeholders in the region over the three years, and I hope I have made some small contribution to the future prosperity of the region," Ms Tetlow added.

Ms Tetlow has taken a shareholding in a food manufacturing business with her husband, but will still have "some time for other interesting projects that might come along".

Prior to her NTDC role, Ms Tetlow was the Launceston Chamber of Commerce's executive officer for the three years to April 2016.

She had previously worked in project management for the City of Launceston council, was chief executive of the Northern Territory government's tourism body, and is a non-executive director of Meru Foods, according to her LinkedIn profile.

NTDC chair John Pitt said he had accepted Ms Tetlow's resignation "with regret", adding she would be missed by the organisation's council members and stakeholders who wished her "every success" for the future.

"Maree has been the driver of the Regional Economic Development Strategy and negotiated the difficult task of securing the support of three levels of government as well as the private sector and other stakeholders," he said.

"It has been a most difficult process - and it's to her absolute credit that we have moved the dial as far as we have to this point. Not just the strategic document but the journey we have travelled to gain some agreement on where our economic future lies."

The NTDC's draft development strategy, released on October 1, identified six priorities to improve the region's economic outcomes.

These included increasing exports, population, innovation and productivity, and private and public investment. Developing a pipeline of projects across both sectors and monitoring the health, well-being and education rates of the community would also be included.

The agency lobbied federal election candidates to fund key projects in the lead up to the election in May.

The municipalities of Launceston, George Town, Flinders, Break O'Day, West Tamar, Meander Valley and the Northern Midlands are owners of the body.

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