Northern Hawks broke out to a commanding lead against Karana before an injury forced an abrupt end to their clash at the Silverdome.
The Hawks were leading 65-16 at three-quarter time when Issy Maskell was sent to hospital with back spasms, leading the umpires to call off the game.
Stand-in Hawks captain Gemma Poke said her fellow defender had been cleared of any serious injury, but would sit out Sunday morning's clash with Kingston.
Poke said she was unsure how points and percentage would be allocated from the game.
Earlier, both sides had been dealt COVID-related blows with Hawks coach Kellie Woolnough and several Flames players unable to take part in the game due to recent travel in Victoria.
With under-19s coach Kellie Tahiri and injured skipper Danni Pickett calling the shots, the Hawks dominated all three terms with shooter Ash Mawer and young gun Kendall Jones combining well in attack.
"Ash Mawer had a really cracking game - she came out of the blocks and stepped up," Poke said.
"She was everywhere, from turning balls over to shooting a heap of goals for us, and Kendall Jones did really well.
"She's new to our opens team this year, but she's definitely getting a lot more opportunity with Danni out for the season and she stepped up and played really well."
There was a much tighter contest on the adjacent court at the Silverdome as Cavaliers fought hard for a 53-45 win over third-placed Cripps Waratah.
Playing for the first time in nearly a month, the home side was beaten out of the blocks as Waratah took a 15-11 lead into the first change.
But a string of unanswered Cavaliers goals resulted in a 14-6 second term, which would ultimately prove the difference.
Cavaliers will meet Karana in an 11am fixture at the Silverdome on Sunday, with the Hawks to host Kingston in the same timeslot.
In the under-19s games, Karana defeated the Hawks 34-31, while Cavaliers overcame Cripps Waratah for the first time this season with a 54-39 win.