The Tasmania Devils and Launceston Tornadoes were within 24 hours of their first games in three weeks, however, the latest outbreak of COVID-19 has put a stop to the matches.
The Devils were due to face Calder Canons in their round 13 NAB League clash in Victoria, while the Torns were set to host Waverly Falcons at home in their NBL1 South return.
The cancellation of the weekend's games comes after a snap seven day lockdown was announced on Thursday in Victoria, that has resulted in a Tasmanian border closure with the state.
A decision to cancel this weekend's interstate trip was one AFL Tasmania North-West talent manager Jamie Hayward said was made sooner rather than later, anticipating the worst.
"We'd done a really good job in building a bit of momentum back up to play Calder; we'd planned and had everything in place ready to go," Hayward said.
"And then we found this out. But we see this as another little bump in the road.
"This is where you're just not over the line until you're over the line."
The sudden changes to games is one players have come to expect - already having had three games cancelled this season - and it's something Hayward said had helped with players' resilience.
"They're building a real sustained level of resilience but I think that's all of us (coaching staff) too," he said.
"We've got some really good support structures for any individual that is particularly affected by the disruption.
"And the advantage we have is that the boys still get to play footy."
Taking to social media to share the news, the Tornadoes were disappointed by the outcome for the club and supporters.
With hopes the mainland state across the Bass will be reopen within a week, Hayward said Devils staff would continue working toward future games.
"We'll start next week planning if we're playing; we've created some really good habits to continue looking forward," he said.
"And that's thinking about the NAB League teams, who knows what opportunities we can create."