UPDATE - 12:22pm
The rider is being flown by helicopter to the Royal Hobart Hospital.
Police say the highway will likely be closed until 4pm
Police are on the scene of a serious motorbike crash on the West Coast.
Serious injuries have been reported and the Westpac Rescue Helicopter has been deployed.
Police say the crash occurred on the Zeehan Highway, just near Tom Creek between Zeehan and Queenstown.
The highway has been closed in both directions.
Police are diverting motorists at the intersection of the Murchison and Zeehan highways through Strahan, and turning drivers around at the Anthony Road intersection.
They say the road will likely be closed for several hours while the scene in cleared.
More to come.