Bracknell redeemed last year's preliminary finals loss, defeating Trevallyn Blue by 12 runs.
The victors made 7-104, led by Bridie Goodluck (17), while Monique Booth's bowling figures (2-14 off four) were tidy.
The runs proved to be too much despite Kellie Scott's (22*) best efforts as skipper Amy Buettel took 3-1 off her four overs.
Beauty Point enjoyed a win on debut, beating fellow first-timers Exeter by nine wickets.
In a match that featured seven 25-ball retirements, Exeter batted first and made a respectable 2-91, which the Tigers chased down in the 15th over.
Carrie Tasker led the way with bat (19*) and ball (1-12) for the victors on their home ground.
Fellow Tamar Valley debutants Beaconsfield weren't able to emulate Beauty Point's feats in their first match, going down to Trevallyn Gold by 36 runs.
Amanda Clark's 10 was the sole double-figure showing in the contest at Trevallyn made 5-78, defended by a clinical bowling spell from Layla Stonehouse, who took 4-3.
Beaconsfield's Tessa Bishop finished with 3-16.
Reigning premiers Longford, who are gunning for four flags in a row, started their defence off strong with a nine-wicket win over Hadspen.
The Tigers' bowling innings, where they left Hadspen at 7-63 off 20 overs, was a Humphries spectacular with captain Emma (2-8), Karlee (2-12) and Haylee (1-5) all playing prominent roles.
Longford coach Stacey Norton-Smith (27) steered the ship home as Hailee Harris (1-21) took the sole wicket.
The closest game of the round saw Evandale Panthers sneak home on the penultimate ball to win by four wickets against ACL.
Batting first, the Bluebacks made 9-92, led by captain Narine Maurangi's unbeaten 35, before she also starred with the ball (3-13).
However, Belinda Prior's 21 and Kaye Buchanan's 19 set the Panthers up for a memorable win to start their season.
George Town's Female Boom debut was abandoned against Legana.
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