Tasmania's newest Senator Wendy Askew will take her place in the chamber on the biggest Parliamentary day of the year - budget day.
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Ms Askew was confirmed as a replacement for her brother David Bushby after a two-week, pre-selection process which saw seven candidates vie for the position before the Liberal Party's pre-selection board.
Her position was approved by Governor Kate Warner on Wednesday.
Ms Askew said she had worked in a variety of private and public sector roles over her career which included 20 years in the banking, time spent as general manager at St Giles and in various government advisory roles.
This included work within the Social Services and Veterans Affairs portfolios.
Ms Askew also worked as an adviser for Will Hodgman when he was opposition leader.
She said based on this experience, she wanted to make sure disadvantaged Tasmanians were not forgotten.
"As a manager in a bank, I've seen people struggling or small businesses fail and I've seen small businesses succeed in ways we didn't expect them to," Ms Askew said.
She said she decided to enter politics as a public figure because the time felt right, having raised her children into adults.
"I've been asked previously on occasions but the time in my life then wasn't right," Ms Askew said.
"I've got to a point where I'm capable of giving the full commitment that is required and I'm conscious of the work that is involved."
She will be sworn into the Senate on April 2 and is due to deliver her maiden speech the following day.
This is likely to be the last sitting day before the federal election.
Ms Askew will serve in the Senate until June 30, 2022 - around the time the next half-senate election is due to be called.
Mr Bushby announced his resignation in January after 11 years as a senator.
He was soon after appointed Australia's consul-general to the United States.
Mr Bushby and his family will be based in Chicago.