A 54-year-old woman has been killed in a two-vehicle crash at Campania early this morning.
Tasmania Police Crash Investigation Services will be investigating the crash on Colebrook Road, near Tea Tree Road.
The road is expected to be blocked for several hours.
Emergency services are also on the scene of a truck rollover on Golconda Road at Lebrina in the state's North.
Police say that it appears that the truck has lost control and rolled as it left the road. The driver of the truck in uninjured and the road will be closed for at least two hours while the vehicle is up-righted.