Two buses will visit 23 townships across Tasmania's North, North-East, North-West, West Coast, Southern Midlands and Central Highlands over a three-week period.

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People aged 12 and over can turn up on the day without an appointment and receive a Pfizer vaccination aboard the bus.

The service will return to each township three weeks later to deliver the second dose.

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RFDS Tasmania chief executive John Kirwan said the program would help ensure that every eligible Tasmanian had the opportunity to protect themselves against COVID-19.

"This is an incredibly important role for the RFDS to play in reaching our rural and remote communities with Covid-19 vaccines," he said.

"The RFDS already takes vital health services and provides health care in these regions, so it is best placed to carry out this work.

"We look forward to working our way through the Tasmanian communities to ensure as many people as possible take up the opportunity to get vaccinated."

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The two buses - donated to the RFDS in 2020 by the state government - have been transformed into mobile health clinics staffed by RFDS staff and volunteers as well as Department of Health immunisers.

RFDS Tasmania primary health care manager Judah Morris encouraged people to take advantage of the service in their local community.

"We'll be in remote and regional towns across the state and now is the time for people who haven't had access to vaccines to get themselves protected," he said.

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