Sean Harris and Tom Waller are the leading candidates to replace Doug Ryan as opener as South Launceston look to bounce back from a tough loss at Sheffield.
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The Knights were forced to make do without star quick Josh Freestone, who pulled up sore at training, and battled at the crease with only Ishang Shah and Nathan Philip tallying double figures.
"It was a really disappointing performance last week against Sheffield - they were quality and they took the game to us," Harris said.
"We're really excited about being back on our home ground this week against Wynyard.
"They've got a couple of decent opening bowlers and Gregg Sharman who'll bat in the middle order ... he can go big so we know they've got some dangerous players."
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Jeremy Jackson and Ben Jackson will return, with last week's late-call-up Alex Licht a chance to make way.
The pharmacist took 1-26 on his Knights debut after arriving from Wynyard in the off-season.
"I'm not 100 per cent sure whether he's going to play this week or not ... [but] we were really pleased with the way he bowled last week," Harris said.
WESTBURY continues to work through what its best XI looks like on the back of an exciting win over Burnie.
Experienced trio Alex Kerrison, Corey Briggs and Liam Ryan will return to strengthen the Shamrocks for a trip to Devonport, who lose star opener Miles Barnard to the Greater Northern Raiders.
"[We're] finding out different player roles and how they come together," Murfet said.
"Until we play plenty of cricket we won't know what the right mix is - a little bit of experimentation along with some added confidence from last week hopefully will help us this Saturday.
"The guys that came in last week in Matty Allen and [Jordan French] and Alex Jordan, they all played really well in their own right but at the same time these other guys that have come back in have put work in behind the scenes and done stuff in the past to earn their spot."
Murfet said coach Matthew Battle, who became a father earlier this year, would return to the side when the time was right.
The lure of three consecutive wins has RIVERSIDE excited for a clash with Burnie.
"Tuesday night was a really good night at training so we're up and about for three and a row, that's our goal," captain Tom Garwood said.
"It was a good win last week only losing two wickets so we'll take some momentum out of that and our top four is doing what we've been asked to do which is really good to see."
Garwood and Matthew Kerrison will replace James Simpson (Raiders) and Bailey Hunt (unavailable), while Ben Kidd is on the cusp of selection following a match-winning 63 in the seconds.
"Ben dropped back not due to form or anything like that, just due to how our side fitted going into the Ulverstone game," Garwood said.
"He did exactly what we asked him to do - go back and make runs - and there's probably three or four guys in our second grade team putting their hand up."
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A win on the road to Ulverstone will do plenty to enhance table-topping LAUNCESTON's status as a genuine cup contender.
The Lions have struggled in the North-West in recent seasons but boast a red-hot Dihan Cloete and an in-form top order of Cam Lynch, Dilan Sandagiridoga, Alistair Taylor and James Lee.
"It's probably a strength of ours our top four or five batters - its good the lower order boys aren't batting too much, it means we're doing our job in the top of the order," Taylor said.
"The batters are there to get the runs, the bowlers are there to take the wickets and I think both parties are doing their job for us so far."
MOWBRAY are poised to take an unchanged line-up into a tough clash with North-West heavyweight Latrobe.
The Eagles were potent with the ball against Devonport but need to find help for skipper Luke Scott, who averages 115 from two innings.
"Normally you want one person from your top five to bat really deep towards the back end of the 40 overs, but at the current point in time we're really looking for two of the top six to bat deep," coach James Storay said.
"We just need someone in the top six to bat with Luke - we're looking for people that want to dig in and really tough out to get a good score."
All five games begin at 10.30am on Saturday.
FIXTURE LIST
- Mowbray v Latrobe (Invermay Park)
- Riverside v Burnie (Riverside)
- Ulverstone v Launceston (UCI Oval)
- South Launceston v Wynyard (NTCA No.2)
- Devonport v Westbury (Devonport)