Northern heavyweights Scotch Oakburn and St Pats have both tasted defeat in the opening rounds of the SATIS football competition.
Champions from 2011-17, St Pats took an early lead in its round one home clash with Guilford Young College before being overrun 7.3 (45) to 6.2 (38).
Clarence pair Ollie Davis and Lachlan Borsboom (two last-term goals) were among the visitors' best while Sam Foley, Tony Aganas and Ollie Sanders (two goals) performed well for St Pats.
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Guilford then followed up with a 25.11 (161) to 1.1 (7) thumping of Launceston Grammar in the state's South on Saturday.
Grammar had a pre-match visit from ex-pupil and Cricket World Cup winner James Faulkner but struggled despite the best efforts of Will Gibson, Jack Colgrave and Thomas Beaumont, who kicked the side's sole major.
Noah Holmes, who stunned North Launceston with four goals just a fortnight ago, kicked a lazy dozen for Guilford.
St Pats evened up its ledger at 1-1 last Wednesday with a 100-point win over reigning premier Scotch Oakburn.
Foley was again best on ground in the home side's 19.7 (121) to 3.3 (21) victory, with Zach Morris (three goals) and Angus Jefferies also influential.
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Jackson Callow topped a list of 10 goal-kickers with a bag of four, while North Launceston's Oliver and Declan Chugg combined for five majors.
Will O'Toole and Ollie Gibson were Scotch Oakburn's best performers.
This weekend's sole fixture sees Grammar host St Pats at 1.30pm on Saturday.