For the last 40 years Trowunna Wildlife Sanctuary has been a pioneer for Tasmanian Devil's conservation, breeding and friendly-image worldwide.
When facial tumours began affecting devils in 2006, Trowunna had been breeding devils for 20 years already.
Owner Androo Kelly said in 2006 when it happened the sanctuary was world's ahead of the rest of the country in breeding devils.
"I had 34 devils here and no one in Tasmania had more than four," he said.
"We've worked to change the image of devils and the fact they are a very shy and timid animal, rather than the vicious animal people perceive them to be.
"We've changed the way devils can be managed and we've taught literally the world that."
Mr Kelly said the sanctuary had bred more than 500 devils for 19 generations through studbook breeding, for a genetically robust and least related kinship system.
"It's the longest breeding program of any Australian native animal," he said.
"We were the ones that taught and trained everyone else on how to care and how to breed devils, that's what we're renowned for."
For the last 15 years he has conducted two courses a year, to about 200 participants from parks, zoo and sanctuaries, to teach them devils best practice and management.
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The Wright's opened the Tasmanian Wildlife Park and Koala Village in 1979 before Mr Kelly took ownership in 1993.
"I changed the name to Trowunna to reflect the nature of us being completely endemic Indigenous, the word is an Indigenous word that means heart and home," he said.
"The Wright's established it to try and break the myth that devils couldn't be tame or friendly, in a sense so people could actually touch them...the starting point of having that ability to interact with animals was pioneered here.
"We want people to interact but we don't want to exploit the animal...everything we do the animal comes first."
In 2006 the sanctuary delivered four devils to Copenhagen Zoo for the birth of Denmark's Crown Princess Mary and Crown Prince Frederik's first child Prince Christian.
The sanctuary has also rehabilitated 163 orphaned wombats back into the wild and breeds threatened Spotted Tail Quolls and vulnerable Eastern Quolls.
Mr Kelly said Eastern Quolls could produce six young in their short life span but had become extinct on the Australian mainland in the 1960s.
"Eastern Quolls' are considered vulnerable in Tasmania and we may see their status go from vulnerable to endangered within a couple of years, that's how quickly it can happen," he said.
"We're involved in a trial program where we've been releasing these species back to Booderee National Park in NSW, near Jervis Bay."
He said they had sent 40 to Trowunna since the trial began and were looking to send another 20 this year but after would look to release them locally in areas with declining populations.
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