Tasmanian senators have been urged by the Greens to block planned changes to classification of genetically modified organisms which they say will hurt Tasmanian primary producers and exporters.
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Proposed federal government legislation will change Gene Technology Act to allow a form of gene-editing not to be classed as a GMO.
The Greens will next month move a disallowance motion against the bill.
Tasmanian Greens senator Nick McKim said in a letter to all senators said the amendment would undermine the state's GMO status.
"Tasmania's GMO-free status underpins so much of our agricultural sector, providing market access and supporting the state's clean and green image," he said.
"Unless disallowed, the new regulations will undermine the state's GMO moratorium, and put us out of step with other jurisdictions, including Europe."
Government minister Richard Colbeck said the regulatory amendments did "not impact the ability of Tasmania to retain a moratorium on genetically modified organisms".
Labor Senator Helen Polley said she would not support any change which would impact the state's interests.
Legislation recently passed through Tasmania's House of Assembly to extend the state's GMO moratorium by 10 years.
Reviews of advancements in GM technology will be taken over that time.