The school provides an online learning platform for those who require schooling from a distance or those with complex needs.

Education Minister Jeremy Rockliff said the four staff members leaving the school had reached the end of their fixed-term contracts, and had also secured permanent positions with other schools.

"Additional eSchool support staff have meanwhile been employed, including school psychologists and social workers with teacher assistant hours also having been increased," Mr Rockliff said.

"Fluctuations in eSchool staffing numbers are common and based on student enrolments and specific needs."

Mr Rockliff maintained the Tasmanian eSchool would continue to operate with staffing levels above the 2016 eSchool review recommendations.

Labor slammed the job removals from the eSchool, with spokesman Josh Willie saying it was an "absolute disgrace the Liberals had targeted these vital services as part of their cruel cuts."

"While Tasmanian schools are waiting for their funding allocations for 2020, Will Hodgman and Jeremy Rockliff are desperately cutting jobs and services to pay for their broken budget," Mr Willie said.

Mr Rockliff denied the teacher departures were part of budget cuts.

"We will not and have not cut funding for students," he said.

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