Fire has destroyed an egg-laying shed at Karoola in the state's North on Wednesday morning.
Thousands of chickens died in the fire.
Tasmania Fire Service crews from Lilydale and Rocherlea attended the scene just after 4.30am.
Upon arrival, fire crews found the 50-metre-wide shed on Brown Mountain Road engulfed in flames.
TFS said quick work by firefighters prevented a nearby shed of equal size containing more chickens from catching fire.
Fire investigators are working to determine the cause of the fire.