A 48-year-old Bridgewater man died on Friday evening in the state’s south.

In the morning, a 59-year-old Victorian man died on the Bass Highway.

The crash in the state’s south happened about 11pm on the Brooker Highway, north of the Elwick Road intersection.

Police say the Bridgewater man was riding a black Harley Davidson from Hobart, towards Bridgewater.

He collided head-on with a white Toyota Corolla sedan, which police say was driving south but in the north-bound lane.

The driver of the car was a 36-year-old Rosetta woman, and she was taken to the Royal Hobart Hospital with minor injuries.

Emergency services attempted to revive the motorcyclist on the scene.

A serious crash also occurred early on Saturday morning at Gagebrook, which has left the three occupants involved with serious and critical injuries.

Police said a silver Holden Barina was travelling east on Baskerville Road at Gagebrook when it left the road and rolled several times.

Police said the car was being driven by a 16-year-old boy, and some of its occupants – four youths and a 19-year-old boy – were not wearing seatbelts.

Tasmania Police crash investigators have asked anyone who witnessed the crashes or who saw the vehicles involved to contact police on 131 444.