Ten of the seizures were made on Tuesday near Ulverstone.

A 43-year-old man will be charged in relation to an unregistered .22 rifle and a 50-year-old man will be charged for possessing a prohibited pump- action shotgun.

Detective Sergeant Michael Foster said eight registered firearms were also seized from the 50-year-old by police.

In a separate incident, police charged an East Devonport man after a search of his home.

Nathan Gregory Coppleman, 22, was charged with breaching a Firearms Prohibition Order.

Police allege that a search of Mr Coppleman's East Devonport residence on Monday found firearms and ammunition.

They said they seized a .22 rifle, a 30-30 rifle and boxes of different types of ammunition in their search.

Mr Coppleman appeared at an out-of-hours court sitting where he was remanded in custody before appearing in the Devonport Magistrates Court on Tuesday.

Operation Unification started on June 16 and will run until Sunday.

Tasmania Police will hold a firearms amnesty at the Sheffield Recreation Ground on Sunday from 9am until 1pm.

"It's basically an opportunity for people with guns or ammunition they don't need or want, or know what to do with, to hand them in," Detective Sergeant Foster said.

Detective Sergeant Foster declined to name the areas on the Central Coast where the seizures were made.