CRAYFISH Creek resident Gloria Theresa Thorpe died as a result of injuries sustained in a three- vehicle crash on the Bass Highway late on Sunday afternoon.
The 57-year-old was one of five people travelling in a 2003 blue Toyota Echo towards Circular Head.
Police said the Toyota crashed into the rear of a black 2013 Nissan Pulsar, which then caused the Toyota to rotate in an anti- clockwise direction onto the wrong side of the road.
It was then struck from the rear by a white 2004 Toyota Hilux towing a trailer.
The dead woman was travelling in the back seat of the Echo.
Another back-seat passenger suffered serious injuries.
The 64-year-old woman was transported to the Royal Hobart Hospital yesterday.
Police said her condition remained serious.
The driver and front-seat passenger of the Toyota Echo, the five occupants of the Nissan and the driver of the Toyota Hilux were all uninjured.
Western District constable Adam Lloyd said investigations into the exact cause of the crash were continuing.
"We don't have a cause as yet because we have only had the chance to interview one person so far," Constable Lloyd said.
He said the name of the seriously injured woman would not be released at the request of her family.
Police would like to speak with anyone who may have witnessed any of the three vehicles involved in the collision on Sunday.
All information can be passed on to Tasmania Police Western Crash Investigation on 131444.