The Launceston-based community health organisation delivers a range of services to people aged 12 to 25 in the state's North and North-West.

It is responsible for the state's branch of youth health service Headspace.

Mr Wightman, a former teacher and principal, will replace Cate Sinclair, who has accepted a role as chief executive of Sydney-based organisation Lifeline Northern Beaches.

Cornerstone chairman Hugh McKenzie acknowledged Mr Wightman's commitment to young people and health.

"Brian brings to Cornerstone a wealth of skill, knowledge and experience in education and government," Mr McKenzie said.

"Access to services and improved outcomes for young people is evidence of the importance of Cornerstone's work and we are excited to welcome Brian to lead the team at Cornerstone in achieving these important outcomes."

Mr Wightman labelled the move to the organisation exciting.

"The challenge is to maintain and grow that commitment to young people by further raising the profile of Cornerstone's work," he said.

"These services are vital not just for young Tasmanians but to the wellbeing of the Tasmanian community."