A caravan was blown over by wind and blocked three-quarters of the Midland Highway for  two hours from about 11.15am.

Driver error was believed to be the cause of a crash about half an hour later, when a Saab sports coupe  and  a Daewoo sedan collided.

About 90 minutes later, a female motorcyclist lost control of her Harley-Davidson   and slid about 20 metres along the Midland Highway.

She was taken to the Launceston General Hospital in a stable condition.

A 32-year-old Chinese woman died in a crash in the state's North-West on Thursday. She was a passenger in a silver Volkswagen hatch that collided with a white Hyundai delivery van.

The woman's 30-year-old husband and driver of the sedan had surgery for multiple injuries.

The second day of police road safety initiative Operation Crossroads was further marred by two crashes in the state's South yesterday.

A boat came off its trailer on the Huon Highway near the Sandfly turnoff and a crash on the Southern Outlet near the Mount Nelson turnoff blocked one lane of traffic.

Acting North-East division inspector Bob Baker said it was crucial that people drove to the conditions.

``There was a lot of traffic on the roads and, given it was fairly wet, that probably contributed, and people should have been driving to the conditions,'' he said.

``People need to be aware there are a lot more cars on the road.''

Tasmania Police said it would continue targeting speeding and drug and alcohol-related incidents throughout Operation Crossroads.

Seven people had tested positive to drugs by Thursday evening, while 11 drink-driving offences were detected from 3404 random breath tests.

 One vehicle had been clamped or confiscated, 97 traffic infringement notices were issued and 31 licence offences were detected.

Operation Crossroads continues until Monday.

Last night Australia's Easter road toll stood at four, with three men killed in crashes in Western Australia.