Police say a caravan has tipped over and will take ''some time'' to clear.

Police have also reported a second crash on the highway, about 4.5 kilometres north of Campbell Town.

This crash has blocked the south-bound lane. Delays are expected.

EARLIER: A crash on the Midland Highway looks set to cause significant delays for Good Friday motorists.

Police reported the crash just after 11am.

The highway is blocked two kilometres south of Campbell Town and is partially blocked in both directions.

Only one lane is in use.

Motorists are advised that traffic is banked up.

MORE TO COME