POLICE hold grave concerns for a Sorell woman missing since early Saturday morning, but say they have no evidence yet to suggest foul play.
Jodi Michele Eaton was last seen at 2.30am on Saturday at a house in Sage Court, Bridgewater.
She had been drinking with friends at the property and had fallen asleep, after refusing her partner's offer to drive her home.
Tasmania Police Inspector Tim Dooley said the last people to see the 28-year-old mother of two were other guests at the gathering, who left about 2.30am.
When the residents of the house woke up about 7am, Ms Eaton had gone.
Inspector Dooley said Ms Eaton had been expected to pick up her children from their father on Saturday morning, but missed the appointment, which she had never done before.
He said her family and partner were extremely concerned for her welfare.
``This is certainly out of character for her,'' Inspector Dooley said.
Inspector Dooley would not say whether police expected to find Ms Eaton alive, but said at this stage it was not a murder investigation.
``We don't have that information at this time,'' Inspector Dooley said.
``As time goes on, we get increasingly anxious that we will find her safe.''
Police searched the suburb on foot and by helicopter today, and also searched the nearby River Derwent.
A police command bus has been set up at the Bridgewater Fire Station, and anyone with information is asked to contact police.